By accessing or using the Aortic Sciences platform, software, and related services (collectively, the "Platform") — including registering for an account, using any calculator, or generating, viewing, or sharing any report — you ("User") agree to be bound by these Terms of Use ("Terms"). Each such use constitutes your acceptance of the then-current Terms. If you do not agree to these Terms in their entirety, you must immediately discontinue use of the Platform and may not generate, share, or rely upon any report.
These Terms constitute a legally binding agreement between you and Aortic Sciences, a corporation organized under the laws of the State of New York.
The Platform is intended solely for use by licensed medical professionals, including but not limited to physicians, nurse practitioners, physician assistants, and other credentialed healthcare providers who are legally authorized to practice medicine in their applicable jurisdiction ("Authorized Users").
The Platform is designed to assist Authorized Users in conducting clinical consultations with patients regarding aortic adverse event risk. All outputs, calculations, risk assessments, and reports are intended exclusively as a clinical consultation tool to support — not replace — the independent medical judgment of a licensed healthcare professional.
By registering for or using the Platform, you represent and warrant that you are a licensed medical professional or credentialed healthcare provider authorized to practice in your applicable jurisdiction, that you are accessing the Platform solely in that professional capacity, and that the Platform is not intended for, and you will not use it for, patient self-assessment or use by members of the general public.
THE PLATFORM DOES NOT PROVIDE MEDICAL ADVICE, DIAGNOSIS, OR TREATMENT.
All risk assessments, projections, multipliers, and recommendations generated by the Platform are:
The Platform is intended to operate as non-device Clinical Decision Support software under Section 520(o)(1)(E) of the Federal Food, Drug, and Cosmetic Act. It applies published, guideline-derived methodology to clinical values manually entered by an Authorized User, presents risk information and options for the Authorized User's independent review, and does not acquire, process, or analyze medical images or signals from any diagnostic or signal-acquisition device.
The Platform is not a medical device, is not FDA cleared or approved, and is not intended to replace or direct the Authorized User's independent clinical judgment. Every risk factor multiplier, source, and the cumulative calculation are disclosed to the Authorized User so that the basis for any figure can be independently reviewed.
THIS PLATFORM IS NOT DESIGNED FOR USE IN MEDICAL EMERGENCIES.
In the event of a suspected aortic dissection, rupture, or any other acute cardiovascular emergency, Authorized Users must immediately direct patients to call 911 or the applicable local emergency services number, or transport the patient to the nearest emergency department.
The risk calculation methodology employed by the Platform is based upon published peer-reviewed medical literature. Primary sources include Elefteriades & Davies (Ann Thorac Surg 2002), Coady et al. (1999), Hagan et al. IRAD (JAMA 2000), Pape et al. (JACC 2007), and ACC/AHA 2022 Guidelines.
RISK FACTOR MULTIPLIERS, GROWTH RATE DEFAULTS, AND CALCULATION PARAMETERS ARE SUBJECT TO CHANGE AT ANY TIME. Aortic Sciences reserves the right to update, revise, or recalibrate any risk factor multiplier, base annual rate, growth rate default, cumulative risk formula, combined-multiplier cap, threshold value, or other calculation parameter or methodology, at its sole discretion and without prior notice. Users are responsible for reviewing the current methodology prior to clinical use. Changes to the methodology do not affect previously generated reports.
The application of risk factor multipliers represents the authors' interpretation and synthesis of published data. These multipliers have not been independently validated in a prospective clinical trial and should be interpreted accordingly.
The Platform provides designated fields for Authorized Users to manually record surgical risk estimates they have independently obtained from third-party tools, including the STS Ascending Aorta & Aortic Root Surgery Risk Calculator (Society of Thoracic Surgeons). Third-party risk estimates entered by the Authorized User may appear in Platform-generated reports solely as a record of that physician's independently obtained clinical data.
Any third-party risk estimates appearing in Platform-generated reports represent clinical data manually entered by the Authorized User and constitute that physician's own clinical input — not a calculation or output of Aortic Sciences. The Authorized User is solely responsible for independently accessing any third-party calculator and for the accuracy of any values entered. Aortic Sciences makes no representations regarding the accuracy, completeness, or currentness of any third-party calculator outputs or the data derived therefrom.
Reference to third-party tools within the Platform does not imply sponsorship, affiliation, endorsement, or approval by those organizations. All third-party trademarks, service marks, and logos are the property of their respective owners. Authorized Users are responsible for compliance with any terms of service applicable to third-party tools they use in connection with the Platform.
Aortic Sciences expressly disclaims all liability for any clinical decisions made in reliance upon data entered from third-party calculators. The Authorized User assumes sole responsibility for the accuracy of any third-party data entered into the Platform.
The Platform operates exclusively with de-identified clinical parameters. Authorized Users must not enter any personally identifiable information (PII) or protected health information (PHI) into any field of the Platform, including but not limited to patient names, dates of birth, Social Security numbers, medical record numbers, or any other direct patient identifiers.
The Platform is designed to be HIPAA Safe Harbor compliant. Risk assessments are generated from de-identified inputs including aortic size, growth rate, age bracket, sex, and clinical risk factors. Authorized Users are solely responsible for ensuring that all data entered into the Platform complies with applicable HIPAA, state, and institutional privacy requirements.
THE PLATFORM IS PROVIDED ON AN "AS IS" AND "AS AVAILABLE" BASIS WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED. Aortic Sciences expressly disclaims all warranties, including implied warranties of merchantability, fitness for a particular purpose, or non-infringement. The risk calculations are derived from population-level statistical data. Individual patient outcomes may vary materially from any population-based estimate.
TO THE MAXIMUM EXTENT PERMITTED BY APPLICABLE LAW, AORTIC SCIENCES SHALL NOT BE LIABLE FOR any direct, indirect, incidental, special, consequential, or punitive damages arising out of use of the Platform, including any clinical decision made in reliance upon Platform outputs, any adverse patient outcome, or any errors or omissions in the risk methodology or calculations.
You agree to indemnify and hold harmless Aortic Sciences, its directors, officers, employees, and agents from and against any claims, damages, losses, costs, and expenses arising out of your use of the Platform, your violation of these Terms, or any clinical decision made in reliance on Platform outputs.
The Platform is currently intended for use within the United States only. Users outside the United States access it at their own risk without guarantee of compliance with local laws or regulations.
Aortic Sciences reserves the right to modify these Terms at any time. Continued use of the Platform following notice of any modification constitutes acceptance. These Terms shall be governed by the laws of the State of New York.